Search results for "Angiotensin inhibitors"

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Experimental Study of the Effects of EIPA, Losartan, and BQ-123 on Electrophysiological Changes Induced by Myocardial Stretch

2015

[ES] Introducción y objetivos Se han implicado diversos mecanismos en la respuesta mecánica al estiramiento miocárdico, que incluyen la activación del intercambiador Na+/H+ por acciones autocrinas y paracrinas. Se estudia la participación de estos mecanismos en las respuestas electrofisiológicas al estiramiento agudo miocárdico mediante el análisis de los cambios inducidos con fármacos. Métodos Se analizan las modificaciones de la fibrilación ventricular inducidas por el estiramiento agudo miocárdico en corazones de conejo aislados y perfundidos utilizando electrodos múltiples epicárdicos y técnicas cartográficas. Se estudian 4 series: control (n = 9); durante la perfusión del antagonista d…

Endothelin Receptor AntagonistsAngiotensin receptorINGENIERIA MECANICAArritmiaAngiotensin II receptor antagonistPharmacologyAmiloridechemistry.chemical_compoundReceptorBiomechanical stressMapeoDrugsHeartGeneral MedicineElectrophysiologyLosartanMappingFármacosCardiologyRabbitsmedicine.symptomEndothelin receptorPerfusionArrhythmiamedicine.drugmedicine.medical_specialtySodium-Hydrogen ExchangersPeptides CyclicLosartanEndothelinElectrofisiologíaTECNOLOGIA ELECTRONICAEndotelinaStress PhysiologicalInternal medicinemedicineEpithelial Sodium Channel BlockersAnimalsVentricular fibrillationFibrilación ventricularFibrillationBQ-123Investigación básicabusiness.industryMyocardiumInhibidores de la angiotensinachemistryAngiotensin inhibitorsMiocardioEstrés biomecánicombusinessBasic researchAngiotensin II Type 1 Receptor Blockers

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PEPhysical Sciences and Engineering
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